The recognized effect of those PTMs on ATXN2’s function and SCA2 pathogenesis continues to be constrained. In other polyQ disorders, many experiments prompt that proteolytic cleavage of polyQ proteins could Enjoy a vital position in pathogenesis [36, 45]. Aligned using this thought, the presence of the enriched 42 kDa fragment while https://neoglycyrol33210.onzeblog.com/28298921/5-essential-elements-for-kukoamine-a