At present, There's two forms of scientific studies on itaconate: Irg1−/− macrophages along with the regulatory impact of itaconate derivatives. Both of these outcomes were being complementary and unveiled that the regulatory mechanisms of itaconate included alkylation on Keap1 to activate Nrf2, succinate dehydrogenase inhibition, activating transcription component 3 (ATF3) https://chancewgrak.acidblog.net/60914772/not-known-details-about-tgf-beta-1-protein