Gastrointestinal (GI): NSAIDs that block COX-one action have correlations with GI issues because of the inhibition from the synthesis of gastroprotective agents for example PGE2 and also other prostaglandins. This inhibition results in lessened mucin production by gastric epithelial cells, fewer bicarbonate secretion, and less epithelial mobile turnover, between other https://ericar367wzb3.hazeronwiki.com/user