Inadequate/Substantial Metabolizers, CYP2D6 The formation from the Lively metabolite, M1, is mediated by CYP2D6, a polymorphic enzyme. Close to seven% of the population has lowered action with the CYP2D6 isoenzyme of cytochrome P450 metabolizing enzyme program. These folks are “inadequate metabolizers” of debrisoquine, dextromethorphan and tricyclic antidepressants, among the other https://jolener998hqy8.wikiexcerpt.com/user